1. Antihypertensive Drug
نویسندگان
چکیده
منابع مشابه
Drug interactions of antihypertensive agents
Adverse drug-drug interactions may occur when a major therapeutic mechanism of one drug class (such as bradycardia with a beta blocker) is excessively exaggerated by the addition of another heart-rate slowing antihypertensive, such as verapamil. The most important interactions at the molecular level are those of the hepatic enzyme, cytochrome (CYP) 3A4. A classic example is the inhibitory effec...
متن کاملPersistence to antihypertensive drug classes
The aim was to study persistence to, and switching between, antihypertensive drug classes and to determine factors associated with poor persistence.This was an observational cohort study. The Swedish Primary Care Cardiovascular Database includes data from medical records, socioeconomic data, filled prescriptions, and hospitalizations from national registries for 75,000 patients with hypertensio...
متن کاملTrends in antihypertensive drug treatment.
To the Editor: It is disappointing to read once again that “b-blockers and thiazide diuretics are the only antihypertensive agents that have been shown to reduce cardiovascular mortality.”1 In these days of evidence-based medicine, we must ask: where is the evidence for this statement? The basic data referenced by Wang et al1 are those of the meta-analysis of Psaty et al,2 which are also shown ...
متن کاملAppraisal of antihypertensive drug therapy.
SUMMARY Four completed prospective studies of drug-treated and control hypertensives utilizing double blind ran-domized protocols are reviewed for the purpose of evaluating the evidence on which the present therapeutic crusade is based. Patients studied were predominantly male, observed for short period, had complications or died at young age, had high incidence of previous target organ vascula...
متن کاملIndividualization of Antihypertensive Drug Treatment
Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation. However, this approach was appropriate decades ago when several drugs had inconveniences that made their use in monotherapy inadvi...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2017
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.106.202